We have witnessed a remarkable transformation in our understanding of the brain and behavior in health and disease over the past 40 years. Extraordinary advances in technology have revolutionized our ability to address fundamental questions about how the brain works. Translating that knowledge into therapeutic discoveries awaits the next generation of physicians. In this Commencement Forum talk, titled "​Awakening Psychiatry and the Doubting Disease," Professor Steven Rasmussen will focus on a common neuropsychiatric illness—obsessive compulsive disorder—to illustrate past advances and future challenges in the field. The event begins at 9 a.m. in Smith-Buonanno Hall, Room 106, 95 Cushing St.